Glucuronic Acid Impurity 4 - Names and Identifiers
Name | L-Glucono-1,5-lactone
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Synonyms | L-Glucono-1,5-lactone L-GLUCONO-1,5-LACTONE L-Gluconicacid,d-lactone Dapagliflozin Impurity 76 L-Gluconic acid, δ-lactone Glucuronic Acid Impurity 4 DELTA-LACTONE-L-GLUCONIC ACID (3S,4R,5R,6S)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-one
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CAS | 52153-09-0
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Glucuronic Acid Impurity 4 - Physico-chemical Properties
Molecular Formula | C6H10O6
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Molar Mass | 178.14 |
Density | 1.3253 (rough estimate) |
Melting Point | 142-144°C(lit.) |
Boling Point | 230.35°C (rough estimate) |
Solubility | DMSO (Slightly), Water (Slightly, Sonicated) |
Appearance | Solid |
Color | White to Off-White |
pKa | 12.13±0.70(Predicted) |
Storage Condition | Refrigerator |
Refractive Index | 1.5860 (estimate) |
Glucuronic Acid Impurity 4 - Introduction
L-Glucono-1,5-lactone(L-glucuronolactone) is an organic compound with the chemical formula C6H10O6. It is a white crystalline powder, soluble in water.
L-Glucono-1,5-lactone is mainly used as a food additive. It is an acidic substance and can be used as a sour agent, chelating agent and antioxidant. In food, it is often used in bread, cakes, fruit vinegar, jelly, beverages and other foods, as a flavoring agent and preservative.
The common method for preparing L-Glucono-1,5-lactone is to generate gluconic acid through the oxidation reaction of glucose, and then perform lactonization reaction under acidic conditions to obtain the product.
Regarding safety information, L-Glucono-1,5-lactone is widely regarded as a safe food additive. It is approved by the FDA (Food and Drug Administration) and other relevant agencies for use in food, is non-toxic and safe to eat. However, in the use of the process should be strictly controlled, in accordance with the relevant provisions of the country and region. For certain groups of people, such as those who are sensitive to gluconic acid or have a history of allergies to lactone, it may be necessary to avoid foods containing L-Glucono-1,5-lactone. If there are any symptoms of discomfort or allergic reactions, you should immediately discontinue use and consult a doctor.
Last Update:2024-04-09 20:13:35